Pancreatic and Duodenal Homeobox 1 (PDX1) (N-Term) Peptide
PDX1
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all PDX1 products
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pdx1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Synonyms
- GSF Peptide, IDX-1 Peptide, IPF1 Peptide, IUF1 Peptide, MODY4 Peptide, PDX-1 Peptide, STF-1 Peptide, ipf1 Peptide, PDX1 Peptide, IPF-1 Peptide, Ipf1 Peptide, Mody4 Peptide, pdx-1 Peptide, Idx1 Peptide, Stf1 Peptide, zgc:100874 Peptide, XlHbox-8 Peptide, xlhbox8 Peptide, pancreatic and duodenal homeobox 1 Peptide, pancreatic and duodenal homeobox 1 S homeolog Peptide, PDX1 Peptide, pdx1 Peptide, Pdx1 Peptide, pdx1.S Peptide
- Background
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Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Alias Symbols: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Protein Size: 284 - Molecular Weight
- 31 kDa
- Gene ID
- 18609
- NCBI Accession
- NM_008814, NP_032840
- UniProt
- P52946
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