Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (C-Term) Peptide
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- Target See all PDIA3 products
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDIA3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
- Synonyms
- ER60 Peptide, ERp57 Peptide, ERp60 Peptide, ERp61 Peptide, GRP57 Peptide, GRP58 Peptide, HsT17083 Peptide, P58 Peptide, PI-PLC Peptide, grp-58 Peptide, 58kDa Peptide, Erp Peptide, Grp58 Peptide, PDI Peptide, PDI-Q2 Peptide, PLC[a] Peptide, Plca Peptide, 1 Peptide, 25D3-membrane-associated Peptide, sb:cb825 Peptide, erp57 Peptide, grp58 Peptide, pdia3 Peptide, protein disulfide isomerase family A member 3 Peptide, protein disulfide-isomerase A3 Peptide, protein disulfide isomerase associated 3 Peptide, protein disulfide isomerase family A, member 3 Peptide, protein disulfide isomerase family A member 3 S homeolog Peptide, PDIA3 Peptide, Tsp_10062 Peptide, Pdia3 Peptide, pdia3 Peptide, pdia3.S Peptide
- Background
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This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: BACE1,CALR,CANX,BACE1,CALR,CANX,ERO1L,ERP27,GYPC,HLA-A,IFNG,SLC12A3,SLC2A1,STAT3,SUMO4,TAP1,CALR,GYPC,Mapk13,SLC12A3,SLC2A1,STAT3,TAP1
Protein Size: 505 - Molecular Weight
- 56 kDa
- Gene ID
- 2923
- NCBI Accession
- NM_005313, NP_005304
- UniProt
- P30101
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