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Poly(rC) Binding Protein 4 (PCBP4) Peptide

PCBP4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981432
  • Target See all PCBP4 products
    PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PCBP4 antibody (Catalog #: ARP40944_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))
    Synonyms
    Pcbp4 Peptide, zgc:77347 Peptide, wu:fc68f03 Peptide, PCBP4 Peptide, CBP Peptide, LIP4 Peptide, MCG10 Peptide, 1200003L19Rik Peptide, AlphaCP-4 Peptide, poly(rC) binding protein 4 Peptide, pcbp4 Peptide, PCBP4 Peptide, Pcbp4 Peptide
    Background
    PCBP4 is a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

    Alias Symbols: CBP, LIP4, MCG10

    Protein Interaction Partner: A2BP1,PCBP1,QKI,RNF138,LYST

    Protein Size: 424
    Molecular Weight
    47 kDa
    Gene ID
    57060
    NCBI Accession
    NM_020418, NP_065151
    UniProt
    Q9GZT1
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