Paired Box 8 (PAX8) Peptide
PAX8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PAX8 products
- PAX8 (Paired Box 8 (PAX8))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX8 antibody (Catalog #: ARP48088_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PAX8 (Paired Box 8 (PAX8))
- Synonyms
- PAX8 Peptide, XPax-8 Peptide, XPax8 Peptide, pax-8 Peptide, PAX-8 Peptide, Pax-8 Peptide, paired box 8 Peptide, paired box 8 L homeolog Peptide, PAX8 Peptide, pax8 Peptide, Pax8 Peptide, pax8.L Peptide
- Background
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PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: -
Protein Interaction Partner: EP300,ID2,NKX2-1,SMAD3,WBP2,NKX2-1
Protein Size: 450 - Molecular Weight
- 48 kDa
- Gene ID
- 7849
- NCBI Accession
- NM_003466, NP_003457
- UniProt
- Q06710
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