Paired Box 3 (PAX3) Peptide
PAX3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Paired Box 3 (PAX3) products
- Paired Box 3 (PAX3)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX3 antibody (Catalog #: ARP32445_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Paired Box 3 (PAX3) peptide
PAX3 Reactivity: Human, Mouse, Rat, Cow Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Paired Box 3 (PAX3)
- Synonyms
- PAX3 Peptide, cdhs Peptide, hup2 Peptide, pax-3 Peptide, ws1 Peptide, xpax3 Peptide, Pax3 Peptide, pax3 Peptide, pax3b Peptide, xPax3-B Peptide, CDHS Peptide, HUP2 Peptide, WS1 Peptide, WS3 Peptide, Pax-3 Peptide, Sp Peptide, splotch Peptide, zgc:92547 Peptide, paired box 3 Peptide, paired box 3 L homeolog Peptide, paired box 3a Peptide, PAX3 Peptide, pax3 Peptide, pax3.L Peptide, Pax3 Peptide, pax3a Peptide
- Background
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PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Alias Symbols: CDHS, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, WS1, WS3
Protein Interaction Partner: CIB1,DAXX,MEOX1,MEOX2,MITF,MSX1,PAX3,SOX10,SOX8,WWTR1,CNR1,DAXX,IPO13,IPO13,MEOX1,MEOX2,MSX1,POU3F2,PSMD4,RAD23B,Rad23b,SOX10,SOX10,TBP,UBC,Ubc
Protein Size: 484 - Molecular Weight
- 53 kDa
- Gene ID
- 5077
- NCBI Accession
- NM_181458, NP_852123
- UniProt
- Q494Z3
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