Parkinson Protein 7 (PARK7) (C-Term) Peptide
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- Target See all PARK7/DJ1 (PARK7) products
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARK7 antibody (Catalog #: ARP51267_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Synonyms
- DJ-1 Peptide, DJ1 Peptide, CAP1 Peptide, Dj1 Peptide, SP22 Peptide, dj1 Peptide, zgc:103725 Peptide, park7b Peptide, park7 Peptide, park7a Peptide, Parkinsonism associated deglycase Peptide, Parkinson disease (autosomal recessive, early onset) 7 Peptide, parkinson protein 7 Peptide, parkinson protein 7 S homeolog Peptide, parkinson protein 7 L homeolog Peptide, PARK7 Peptide, Park7 Peptide, park7 Peptide, park7.S Peptide, park7.L Peptide
- Background
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PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: DJ-1, DJ1, FLJ27376
Protein Interaction Partner: DAXX,EFCAB6,PARK7,PIAS2,PPP2R1A,PPP2R1B,SUMO1,C19orf62,EFCAB6,PIAS2,USP19
Protein Size: 189 - Molecular Weight
- 20 kDa
- Gene ID
- 11315
- NCBI Accession
- NM_007262, NP_009193
- UniProt
- Q99497
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