Proliferation-Associated 2G4, 38kDa (PA2G4) (C-Term) Peptide
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- Target See all PA2G4 products
- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PDLYKSEMEV QDAELKALLQ SSASRKTQKK KKKKASKTVE NATSGETLEE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pa2g4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
- Synonyms
- EBP1 Peptide, HG4-1 Peptide, p38-2G4 Peptide, Ebp1 Peptide, pa2g4 Peptide, si:dz150i12.2 Peptide, wu:fb19b11 Peptide, wu:ft56d05 Peptide, zgc:86732 Peptide, ebp1 Peptide, hg4-1 Peptide, p38-2g4 Peptide, pa2g4-a Peptide, PA2G4 Peptide, DKFZp469G2132 Peptide, Pa2g4 Peptide, MGC81621 Peptide, 38kDa Peptide, AA672939 Peptide, Plfap Peptide, proliferation-associated 2G4 Peptide, proliferation-associated 2G4, a Peptide, proliferation-associated 2G4, 38kDa Peptide, proliferation-associated 2G4 L homeolog Peptide, proliferation-associated protein 2G4 Peptide, proliferation-associated 2G4 S homeolog Peptide, proliferation-associated protein 2G4 pseudogene Peptide, PA2G4 Peptide, Pa2g4 Peptide, pa2g4a Peptide, pa2g4.L Peptide, pa2g4 Peptide, LOC100519773 Peptide, pa2g4.S Peptide, LOC693641 Peptide
- Background
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Pa2g4 may play a role in a ERBB3-regulated signal transduction pathway. It seems be involved in growth regulation. It acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). It inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. It may be involved in ribosome assembly. It mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). It together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES.
Alias Symbols: 38 kDa, AA672939, Ebp1, Plfap
Protein Size: 394 - Molecular Weight
- 44 kDa
- Gene ID
- 18813
- NCBI Accession
- NM_011119, NP_035249
- UniProt
- P50580
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