Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide
P4HA1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all P4HA1 products
- P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MAKEKDVNKS ASDDQSDQKT TPKKKGVAVD YLPERQKYEM LCRGEGIKMT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-P4HA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
- Synonyms
- P4HA Peptide, AL022634 Peptide, P4ha Peptide, PHalphaI Peptide, prolyl 4-hydroxylase subunit alpha-1 Peptide, prolyl 4-hydroxylase subunit alpha 1 Peptide, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide Peptide, CpipJ_CPIJ000975 Peptide, CpipJ_CPIJ017131 Peptide, Tsp_03346 Peptide, Tsp_03347 Peptide, Tsp_15957 Peptide, P4HA1 Peptide, P4ha1 Peptide
- Background
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This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: P4HA
Protein Size: 516 - Molecular Weight
- 56 kDa
- Gene ID
- 5033
- NCBI Accession
- NM_001142596, NP_001136068
- UniProt
- C9JL12
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