Oxytocin, Prepropeptide (OXT) (N-Term) Peptide
OXT
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OXT products
- OXT (Oxytocin, Prepropeptide (OXT))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-OXT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- OXT (Oxytocin, Prepropeptide (OXT))
- Background
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There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Alias Symbols: MGC126890, MGC126892, OT, OT-NPI
Protein Interaction Partner: ESR2,OXTR,PREP,TXNDC17,MLL,TXNDC17
Protein Size: 125 - Molecular Weight
- 9 kDa
- Gene ID
- 5020
- NCBI Accession
- NM_000915, NP_000906
- UniProt
- P01178
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