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One Cut Homeobox 1 (ONECUT1) (N-Term) Peptide

ONECUT1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981134
  • Target See all ONECUT1 products
    ONECUT1 (One Cut Homeobox 1 (ONECUT1))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ONECUT1 antibody (Catalog #: ARP38480_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ONECUT1 (One Cut Homeobox 1 (ONECUT1))
    Synonyms
    D9Ertd423e Peptide, HNF-6 Peptide, Hfh12 Peptide, Hnf6 Peptide, Hnf6b Peptide, OC-1 Peptide, Oc1 Peptide, onecut Peptide, onecut1 Peptide, id:ibd5005 Peptide, HNF6 Peptide, HNF6A Peptide, HNF-6a Peptide, oc1 Peptide, onecut1l Peptide, zgc:65904 Peptide, zgc:77450 Peptide, one cut domain, family member 1 Peptide, one cut homeobox 1 Peptide, one cut domain, family member, like Peptide, Onecut1 Peptide, onecutl Peptide, ONECUT1 Peptide, onecut1 Peptide
    Background
    ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

    Alias Symbols: HNF-6, HNF6, HNF6A

    Protein Interaction Partner: CREBBP,FOXA2,KAT2B,NR3C1,CREBBP,FOXA1,FOXA2,KAT2B,NR3C1

    Protein Size: 465
    Molecular Weight
    51 kDa
    Gene ID
    3175
    NCBI Accession
    NM_004498, NP_004489
    UniProt
    Q9UBC0
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