Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide
NUMA1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NUMA1 products
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NUMA1 antibody (Catalog #: ARP50532_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Background
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NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
Alias Symbols: NUMA
Protein Interaction Partner: GNAI1,GPSM2,ACTR1A,EPB41,EPB41L1,EPB41L2,GNAI1,GPSM2,NCOA6,PIM1,RAD21,SMC1A,TNKS,YEATS4,ACTR1A,EPB41,EPB41L1,EPB41L2,GPSM2,NCOA6,NPM1,PIM1,RPAP1,SMC1A,SMC3,TNKS,YEATS4
Protein Size: 2115 - Molecular Weight
- 238 kDa
- Gene ID
- 4926
- NCBI Accession
- NM_006185, NP_006176
- UniProt
- Q14980
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