Neuronal Pentraxin II (NPTX2) (N-Term) Peptide
NPTX2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NPTX2 products
- NPTX2 (Neuronal Pentraxin II (NPTX2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VQQKETLGAQ REAIRELTGK LARCEGLAGG KARGAGATGK DTMGDLPRDP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NPTX2 Antibody(ARP56365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NPTX2 (Neuronal Pentraxin II (NPTX2))
- Background
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NARP, NP-II, NP2
Protein Interaction Partner: NPTXR,Nptx1,Nptxr
Protein Size: 431 - Molecular Weight
- 47 kDa
- Gene ID
- 4885
- NCBI Accession
- NM_002523, NP_002514
- UniProt
- P47972
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