Protein AF-9 (MLLT3) Peptide
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- Target See all AF9 (MLLT3) products
- AF9 (MLLT3) (Protein AF-9 (MLLT3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MLLT3 antibody (Catalog #: ARP38489_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AF9 (MLLT3) (Protein AF-9 (MLLT3))
- Synonyms
- fc39c11 Peptide, wu:fc39c11 Peptide, zgc:110210 Peptide, AF9 Peptide, YEATS3 Peptide, 2210011H10Rik Peptide, 2610012I03Rik Peptide, 3830408D16Rik Peptide, Af9 Peptide, D4Ertd321e Peptide, Af-9 Peptide, MLLT3, super elongation complex subunit Peptide, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 Peptide, mllt3 Peptide, MLLT3 Peptide, Mllt3 Peptide
- Background
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MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
Alias Symbols: AF9, FLJ2035, YEATS3
Protein Interaction Partner: AFF1,APPBP2,BCOR,C1orf103,C7orf64,CBX8,EEF1A1,MCM6,MLLT3,PTN,APPBP2,BCOR,C1orf103,C7orf64,DOT1L,EEF1A1,MCM6,PTN,SGK1
Protein Size: 568 - Molecular Weight
- 63 kDa
- Gene ID
- 4300
- NCBI Accession
- NM_004529, NP_004520
- UniProt
- P42568
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