Mediator Complex Subunit 25 (MED25) (N-Term) Peptide
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- Target See all MED25 products
- MED25 (Mediator Complex Subunit 25 (MED25))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
- Sequence
- EGLRKHYLLP AIEYFNGGPP AETDFGGDYG GTQYSLVVFN TVDCAPESYV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED25 Antibody(ARP50698_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED25 (Mediator Complex Subunit 25 (MED25))
- Synonyms
- Arc92 Peptide, CG12254 Peptide, Dmel\\CG12254 Peptide, LD07688 Peptide, Med25 Peptide, dARC92 Peptide, dDrip97 Peptide, med25 Peptide, ACID1 Peptide, ARC92 Peptide, CMT2B2 Peptide, P78 Peptide, PTOV2 Peptide, RGD1305137 Peptide, 2610034E13Rik Peptide, 2610529E18Rik Peptide, ESTM2 Peptide, X83308 Peptide, zgc:63555 Peptide, Mediator complex subunit 25 Peptide, mediator complex subunit 25 Peptide, mediator complex subunit 25 S homeolog Peptide, MED25 Peptide, med25 Peptide, Med25 Peptide, med25.S Peptide
- Background
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This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Alias Symbols: ACID1, ARC92, CMT2B2, DKFZp434K0512, MGC70671, P78, PTOV2, TCBAP0758
Protein Interaction Partner: CDK8,HCFC1,MED1,MED15,MED6,MED8,MED9,TFF1,CDK8,MED1,MED10,MED11,MED15,MED17,MED18,MED19,MED22,MED26,MED28,MED29,MED4,MED6,MED8,MED9,UL48
Protein Size: 747 - Molecular Weight
- 78 kDa
- Gene ID
- 81857
- NCBI Accession
- NM_030973, NP_112235
- UniProt
- Q71SY5
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