Mutated in Colorectal Cancers (MCC) (C-Term) Peptide
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- Target See all MCC products
- MCC (Mutated in Colorectal Cancers (MCC))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SSTSSGSKDK PGKECADAAS PALSLAELRT TCSENELAAE FTNAIRREKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MCC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MCC (Mutated in Colorectal Cancers (MCC))
- Synonyms
- MCC Peptide, mcc1 Peptide, MCC1 Peptide, D18Ertd451e Peptide, E330037C19 Peptide, RGD1561988 Peptide, mutated in colorectal cancers Peptide, MCC Peptide, mcc Peptide, Mcc Peptide
- Background
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This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp762O1615, FLJ38893, FLJ46755, MCC1
Protein Size: 829 - Molecular Weight
- 91 kDa
- Gene ID
- 4163
- NCBI Accession
- NM_002387, NP_002378
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