Macrophage Receptor with Collagenous Structure (MARCO) (C-Term) Peptide
MARCO
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MARCO products
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MARCO Antibody(ARP41581_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Synonyms
- AI323439 Peptide, Ly112 Peptide, Scara2 Peptide, SCARA2 Peptide, macrophage receptor with collagenous structure Peptide, MARCO Peptide, Marco Peptide
- Background
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The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Alias Symbols: SCARA2
Protein Interaction Partner: SCGB3A1,SCGB3A2,SCGB3A1,SCGB3A2
Protein Size: 520 - Molecular Weight
- 53 kDa
- Gene ID
- 8685
- NCBI Accession
- NM_006770, NP_006761
- UniProt
- Q9UEW3
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