Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) Peptide
MARCKS
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MARCKS products
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MARCKS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
- Background
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The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
Protein Interaction Partner: NMT1,CALM3,CTSB,NMT1,PKN1,PRKCA,PRKCB,TOB1,CALM2,CTSB,TOB1
Protein Size: 332 - Molecular Weight
- 31 kDa
- Gene ID
- 4082
- NCBI Accession
- NM_002356, NP_002347
- UniProt
- P29966
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