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Lin-28 Homolog C (LIN28C) (N-Term) Peptide

LIN28C Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN979329
  • Target
    LIN28C (Lin-28 Homolog C (LIN28C))
    Protein Region
    N-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LIN28 antibody (Catalog #: ARP34477_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LIN28C (Lin-28 Homolog C (LIN28C))
    Background
    LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.

    Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A

    Protein Size: 209
    Molecular Weight
    23 kDa
    Gene ID
    79727
    NCBI Accession
    NM_024674, NP_078950
    UniProt
    Q9H9Z2
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