Lysosomal Protein Transmembrane 4 beta (LAPTM4B) (Middle Region) Peptide
LAPTM4B
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all LAPTM4B products
- LAPTM4B (Lysosomal Protein Transmembrane 4 beta (LAPTM4B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LAPTM4B antibody (Catalog #: ARP47442_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LAPTM4B (Lysosomal Protein Transmembrane 4 beta (LAPTM4B))
- Synonyms
- LAPTM4beta Peptide, LC27 Peptide, C330023P13Rik Peptide, lysosomal protein transmembrane 4 beta Peptide, lysosomal-associated protein transmembrane 4B Peptide, LAPTM4B Peptide, Laptm4b Peptide
- Background
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LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
Alias Symbols: LAPTM4beta, LC27
Protein Size: 317 - Molecular Weight
- 35 kDa
- Gene ID
- 55353
- NCBI Accession
- NM_018407, NP_060877
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