Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptide
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- Target See all KIFAP3 products
- KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KIFAP3 Antibody(ARP55127_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))
- Synonyms
- CG11759 Peptide, DmKAP Peptide, DmKap Peptide, Dmel\\CG11759 Peptide, KAP Peptide, KAP3 Peptide, Kap Peptide, dKAP3 Peptide, kap3 Peptide, FLA3 Peptide, KAP-1 Peptide, KAP-3 Peptide, SMAP Peptide, Smg-GDS Peptide, dJ190I16.1 Peptide, fb99h08 Peptide, kifap3 Peptide, wu:fb99h08 Peptide, wz7228 Peptide, Kinesin associated protein 3 Peptide, kinesin-associated protein 3 Peptide, kinesin associated protein 3 Peptide, kinesin-associated protein 3b Peptide, kinesin-associated protein 3 L homeolog Peptide, Kap3 Peptide, LOC551999 Peptide, KIFAP3 Peptide, Kifap3 Peptide, kifap3b Peptide, kifap3.L Peptide
- Background
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The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: APC,KIF3B,KIFAP3,MAP3K10,MINK1,RAP1GDS1,RBFOX1,RPGR,SMC3,SRC,APC,AR,MAP3K10,MAP3K11,RAP1GDS1,SMC3,SRC
Protein Size: 792 - Molecular Weight
- 91 kDa
- Gene ID
- 22920
- NCBI Accession
- NM_014970, NP_055785
- UniProt
- Q92845
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