Interferon Regulatory Factor 6 (IRF6) (Middle Region) Peptide
IRF6
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all IRF6 products
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF6 antibody (Catalog #: ARP31995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Interferon Regulatory Factor 6 (IRF6) peptide
IRF6 Reactivity: Human, Mouse Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- Synonyms
- IRF6 Peptide, lps Peptide, pit Peptide, pps Peptide, vws Peptide, ofc6 Peptide, xIRF-6 Peptide, DKFZp469E012 Peptide, LPS Peptide, OFC6 Peptide, PIT Peptide, PPS Peptide, PPS1 Peptide, VWS Peptide, VWS1 Peptide, zgc:63500 Peptide, AI876454 Peptide, E230028I05Rik Peptide, mirf6 Peptide, interferon regulatory factor 6 Peptide, interferon regulatory factor 6 S homeolog Peptide, IRF6 Peptide, irf6 Peptide, irf6.S Peptide, Irf6 Peptide
- Background
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IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1
Protein Interaction Partner: LBP
Protein Size: 467 - Molecular Weight
- 53 kDa
- Gene ID
- 3664
- NCBI Accession
- NM_006147, NP_006138
- UniProt
- O14896
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