Interferon Regulatory Factor 5 (IRF5) Peptide
-
- Target See all IRF5 products
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Origin
- Human, Mouse
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF5 antibody (Catalog #: ARP37180_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Synonyms
- IRF5 Peptide, irf5 Peptide, SLEB10 Peptide, AW491843 Peptide, mirf5 Peptide, im:7155364 Peptide, zgc:76986 Peptide, interferon regulatory factor 5 Peptide, interferon regulatory factor 5 L homeolog Peptide, IRF5 Peptide, irf5 Peptide, Irf5 Peptide, irf5.L Peptide
- Background
-
The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Alias Symbols: mirf5, AW491843
Protein Interaction Partner: Il12b,Myd88,Traf6
Protein Size: 497 - Molecular Weight
- 55 kDa
- Gene ID
- 27056
- NCBI Accession
- NM_012057, NP_036187
- UniProt
- P56477
-