5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) Peptide
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- Target See all HTR2A products
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTR2A antibody (Catalog #: AVARP13044_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
- Background
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HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: ANKS1B,DLG4,EIF3F,GLUL,GNA11,GNAI1,GNAQ,JAK2,MAP1A,MRPL28,NDUFB10,NME3,NTRK3,PON2,PPP5C,RPS6KA3,DLG4,JAK2
Protein Size: 471 - Molecular Weight
- 52 kDa
- Gene ID
- 3356
- NCBI Accession
- NM_000621, NP_000612
- UniProt
- P28223
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