Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptide
HNRPDL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HNRPDL products
- HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRPDL antibody (Catalog #: ARP40586_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
- Background
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HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.
Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL
Protein Interaction Partner: ATIC,HGS,HNRNPA1,KHDRBS2
Protein Size: 420 - Molecular Weight
- 46 kDa
- Gene ID
- 9987
- NCBI Accession
- NM_005463, NP_005454
- UniProt
- O14979
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