Histone Cluster 2, H4 (HIST2H4) (Middle Region) Peptide
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- Target
- HIST2H4 (Histone Cluster 2, H4 (HIST2H4))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hist2h4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HIST2H4 (Histone Cluster 2, H4 (HIST2H4))
- Synonyms
- H4 Peptide, X04652 Peptide, histone cluster 2, H4 Peptide, histone H4 Peptide, Hist2h4 Peptide, H4 Peptide
- Background
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Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H4, X04652
Protein Size: 103 - Molecular Weight
- 11 kDa
- Gene ID
- 97122
- NCBI Accession
- NM_033596, NP_291074
- UniProt
- P62806
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