G-2 and S-Phase Expressed 1 (GTSE1) (Middle Region) Peptide
-
- Target See all GTSE1 products
- GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GTSE1 antibody (Catalog #: ARP42471_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))
- Synonyms
- gtse1 Peptide, MGC81588 Peptide, MGC89498 Peptide, GTSE1 Peptide, fb70b04 Peptide, fj88g09 Peptide, wu:fb70b04 Peptide, wu:fj88g09 Peptide, wu:fy65d12 Peptide, MGC114722 Peptide, B99 Peptide, Gtse-1 Peptide, RGD1563164 Peptide, G2 and S-phase expressed 1 S homeolog Peptide, G2 and S-phase expressed 1 Peptide, G-2 and S-phase expressed 1 Peptide, G2 and S-phase expressed 1 L homeolog Peptide, G two S phase expressed protein 1 Peptide, gtse1.S Peptide, gtse1 Peptide, GTSE1 Peptide, gtse1.L Peptide, Gtse1 Peptide
- Background
-
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Alias Symbols: B99
Protein Interaction Partner: USP11
Protein Size: 720 - Molecular Weight
- 76 kDa
- Gene ID
- 51512
- NCBI Accession
- NM_016426, NP_057510
- UniProt
- Q9NYZ3
-