Gastrin-Releasing Peptide (GRP) (C-Term) Peptide
-
- Target See all Gastrin-Releasing Peptide (GRP) products
- Gastrin-Releasing Peptide (GRP)
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- Gastrin-Releasing Peptide (GRP)
- Synonyms
- BLP Peptide, GRP Peptide, BN Peptide, GRP-10 Peptide, preproGRP Peptide, proGRP Peptide, gastrin releasing peptide Peptide, Grp Peptide, GRP Peptide
- Background
-
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: BN, GRP-10, preproGRP, proGRP
Protein Interaction Partner: DPP4,GRPR,MEP1A,MEP1B
Protein Size: 141 - Molecular Weight
- 15 kDa
- Gene ID
- 2922
- NCBI Accession
- NM_001012512, NP_001012530
-