Glucose-6-Phosphate Isomerase (GPI) (C-Term) Peptide
GPI
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GPI products
- GPI (Glucose-6-Phosphate Isomerase (GPI))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SFDQWGVELG KQLAKKIEPE LDGSAQVTSH DASTNGLINF IKQQREARVQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GPI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GPI (Glucose-6-Phosphate Isomerase (GPI))
- Target Type
- Viral Protein
- Background
-
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Alias Symbols: AMF, GNPI, NLK, PGI, PHI, SA36, SA-36
Protein Interaction Partner: AMFR,CSNK2A1,GPI,IGFBP3,PARP14,UBC
Protein Size: 558 - Molecular Weight
- 63 kDa
- Gene ID
- 2821
- NCBI Accession
- NM_000175, NP_000166
- UniProt
- P06744
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