Growth Hormone 1 (GH1) (C-Term) Peptide
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- Target See all Growth Hormone 1 (GH1) products
- Growth Hormone 1 (GH1)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TYSKFDTNSH NDDALLKNYG LLYCFRKDMD KVETFLRIVQ CRSVEGSCGF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Growth Hormone 1 (GH1)
- Background
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The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Alias Symbols: GH, GH-N, GHN, IGHD1B, hGH-N
Protein Interaction Partner: GH1,PRLR,BTRC,GHR,LTA4H,SHC1,STRAP
Protein Size: 177 - Molecular Weight
- 20 kDa
- Gene ID
- 2688
- NCBI Accession
- NM_022560, NP_072054
- UniProt
- A6NEF6
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