Glucokinase (Hexokinase 4) Regulator (GCKR) (C-Term) Peptide
GCKR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GCKR products
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PIALLSLLFR CSITEAQAHL AAAPSVCEAV RSALAGPGQK RTADPLEILE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCKR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Glucokinase (Hexokinase 4) Regulator (GCKR) peptide
GCKR Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Background
-
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GKRP, FGQTL5
Protein Interaction Partner: GCK,GCK,TRAF2,UBC
Protein Size: 625 - Molecular Weight
- 68 kDa
- Gene ID
- 2646
- NCBI Accession
- NM_001486, NP_001477
- UniProt
- Q14397
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