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Forkhead Box A2 (FOXA2) (Middle Region) Peptide

FOXA2 Reactivity: Mouse Host: Synthetic BP, WB
Catalog No. ABIN976981
  • Target See all FOXA2 products
    FOXA2 (Forkhead Box A2 (FOXA2))
    Protein Region
    Middle Region
    Origin
    Mouse
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SSGGKKTAPG SQASQAQLGE AAGSASETPA GTESPHSSAS PCQEHKRGGL
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FOXA2 (Forkhead Box A2 (FOXA2))
    Synonyms
    hnf3b Peptide, tcf3b Peptide, hnf3beta Peptide, hnf3-beta Peptide, FOXA2 Peptide, HNF3B Peptide, TCF3B Peptide, HNF-3B Peptide, ax Peptide, axl Peptide, fkd1 Peptide, ik:tdsubc_2g8 Peptide, tdsubc_2g8 Peptide, wu:fe05g04 Peptide, xx:tdsubc_2g8 Peptide, FoxA2-A Peptide, FoxA2a Peptide, xFD-3 Peptide, xbeta-1 Peptide, HNF-3b Peptide, HNF3-beta Peptide, HNF3beta Peptide, Hnf-3b Peptide, Hnf3b Peptide, Tcf-3b Peptide, Tcf3b Peptide, HNF-3BETA Peptide, forkhead box A2 Peptide, forkhead box A2 L homeolog Peptide, foxa2 Peptide, FOXA2 Peptide, foxa2.L Peptide, Foxa2 Peptide
    Background
    Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.

    Alias Symbols: HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b

    Protein Interaction Partner: Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2

    Protein Size: 459
    Molecular Weight
    48 kDa
    Gene ID
    15376
    NCBI Accession
    NM_010446, NP_034576
    UniProt
    P35583
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