F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) (N-Term) Peptide
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- Target See all FBXL2 products
- FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXL2 antibody (Catalog #: ARP43096_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))
- Synonyms
- FBL2 Peptide, FBL3 Peptide, 2810423A21Rik Peptide, Fbl3 Peptide, RGD1562243 Peptide, fbxl20 Peptide, sb:cb783 Peptide, zgc:73374 Peptide, Fbl2 Peptide, Fbxl2 Peptide, F-box and leucine rich repeat protein 2 Peptide, F-box and leucine-rich repeat protein 2 Peptide, F-box and leucine-rich repeat protein 20 Peptide, FBXL2 Peptide, Fbxl2 Peptide, fbxl2 Peptide, Fbxl20 Peptide
- Background
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FBXL2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL2 belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.
Alias Symbols: DKFZP564P0622, FBL2, FBL3
Protein Interaction Partner: SKP1,HCVgp1,COL7A1,SKP1
Protein Size: 423 - Molecular Weight
- 47 kDa
- Gene ID
- 25827
- NCBI Accession
- NM_012157, NP_036289
- UniProt
- Q9UKC9
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