Fibrillin 1 (FBN1) Peptide
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- Target See all Fibrillin 1 (FBN1) products
- Fibrillin 1 (FBN1)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBN1 antibody (Catalog #: ARP37969_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Fibrillin 1 (FBN1)
- Background
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FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.
Alias Symbols: FBN, SGS, WMS, MASS, MFS1, OCTD, SSKS, WMS2, ACMICD, GPHYSD2
Protein Interaction Partner: FBLN2,CALR,DCN,ELN,FBLN2,FBN2,HSPG2,LTBP1,MFAP2,MFAP5,MYOC,VCAN,ELN,FBLN2,MFAP2,MYOC,VCAN
Protein Size: 195 - Molecular Weight
- 21 kDa
- Gene ID
- 2200
- NCBI Accession
- NM_000138
- UniProt
- Q75N89
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