MDS1 and EVI1 Complex Locus (MECOM) Peptide
MECOM
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MECOM products
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EVI1 antibody (Catalog #: ARP31659_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- Synonyms
- AML1-EVI-1 Peptide, EVI1 Peptide, MDS1 Peptide, MDS1-EVI1 Peptide, PRDM3 Peptide, D630039M04Rik Peptide, Evi-1 Peptide, Evi1 Peptide, Jbo Peptide, Mds Peptide, Mds1 Peptide, Mds1-Evi1 Peptide, Prdm3 Peptide, Znfpr1b1 Peptide, evi1 Peptide, im:7140716 Peptide, prdm3 Peptide, evi-1 Peptide, mecom Peptide, mecom-a Peptide, mecom-b Peptide, xEvi-1 Peptide, evi1-B Peptide, MDS1 and EVI1 complex locus Peptide, MDS1 and EVI1 complex locus L homeolog Peptide, MDS1 and EVI1 complex locus S homeolog Peptide, MECOM Peptide, Mecom Peptide, mecom Peptide, mecom.L Peptide, mecom.S Peptide
- Background
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EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Alias Symbols: AML1-EVI-1, EVI-1, MDS1-EVI1, MGC163392, PRDM3, EVI1, MDS1
Protein Interaction Partner: CREBBP,CTBP1,CTBP2,HDAC1,HDAC4,KAT2B,SMAD3,HDAC1,MECOM,CREBBP,CTBP1,HDAC1,HDAC4,KAT2B,MBD3,SMAD3
Protein Size: 1051 - Molecular Weight
- 118 kDa
- Gene ID
- 2122
- NCBI Accession
- NM_005241, NP_005232
- UniProt
- Q03112
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