ECSIT Homolog (ECSIT) (N-Term) Peptide
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- Target
- ECSIT (ECSIT Homolog (ECSIT))
- Protein Region
- N-Term
- Origin
- Mouse
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EPWLVPRPPE PQRKPIKVPA MHEDSFKPSG NRERDKASFL NAVRSFGAHN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ecsit Antibody(ARP37175_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ECSIT (ECSIT Homolog (ECSIT))
- Synonyms
- Sitpec Peptide, ECSIT signalling integrator Peptide, Ecsit Peptide
- Background
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Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Irak1,Map3k1,SMURF1,TRAF6,Traf6
Protein Size: 435 - Molecular Weight
- 50 kDa
- Gene ID
- 26940
- NCBI Accession
- NM_012029, NP_036159
- UniProt
- Q9QZH6
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