Deltex Homolog 3 (Drosophila) (DTX3) (C-Term) Peptide
DTX3
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all Deltex Homolog 3 (DTX3) products
- Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YEKYGTIVIQ YVFPPGVQGA EHPNPGVRYP GTTRVAYLPD CPEGNKVLTL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dtx3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))
- Synonyms
- RGD1566181 Peptide, Deltex3 Peptide, mg310 Peptide, RNF154 Peptide, deltex E3 ubiquitin ligase 3 Peptide, deltex homolog 3 (Drosophila) Peptide, deltex 3, E3 ubiquitin ligase Peptide, Dtx3 Peptide, DTX3 Peptide, dtx3 Peptide
- Background
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Dtx3 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Dtx3 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Dtx3 functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Alias Symbols: Deltex3, MGC106339, mg310
Protein Interaction Partner: Dtx2,Dtx3
Protein Size: 347 - Molecular Weight
- 38 kDa
- Gene ID
- 80904
- NCBI Accession
- NM_030714, NP_109639
- UniProt
- Q80V91
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