Desmin (DES) (Middle Region) Peptide
DES
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Desmin (DES) products
- Desmin (DES)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DES antibody (Catalog #: ARP41483_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Desmin (DES) peptide
DES Reactivity: Human, Rat, Cow, Dog, Pig, Mouse Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Desmin (DES)
- Synonyms
- DES Peptide, des-b Peptide, MGC80853 Peptide, des Peptide, csm1 Peptide, csm2 Peptide, desm Peptide, cmd1i Peptide, MGC75911 Peptide, LOC100220724 Peptide, desmin Peptide, cb290 Peptide, fb59a12 Peptide, wu:fb59a12 Peptide, zgc:109859 Peptide, CSM1 Peptide, CSM2 Peptide, LGMD2R Peptide, wu:fc11d08 Peptide, zgc:154009 Peptide, des-a Peptide, MGC52614 Peptide, desmin Peptide, desmin, gene 1 L homeolog Peptide, desmin, gene 1 Peptide, desmin a Peptide, desmin b Peptide, desmin, gene 1 S homeolog Peptide, desmin, gene 2 S homeolog Peptide, DES Peptide, des.1.L Peptide, des.1 Peptide, des Peptide, desma Peptide, Des Peptide, desmb Peptide, des.1.S Peptide, des.2.S Peptide
- Background
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DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Protein Interaction Partner: CAPN1,AURKB,CAPN1,DSP,NEB,PKD1,ROCK1,S100A1,S100B,SHBG,SPTAN1,SYNC,SYNM,TRIM7,DSP,NEB,S100A1,SPTAN1,SYNC,SYNM
Protein Size: 470 - Molecular Weight
- 53 kDa
- Gene ID
- 1674
- NCBI Accession
- NM_001927, NP_001918
- UniProt
- P17661
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