DBF4 Homolog (DBF4) (C-Term) Peptide
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- Target See all DBF4 products
- DBF4 (DBF4 Homolog (DBF4))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AELDKKRTEY LPAHEDRTCG SPVQSLLDLF QTSEEKSEFL GFTGYTENSG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dbf4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DBF4 (DBF4 Homolog (DBF4))
- Synonyms
- ASK Peptide, CHIF Peptide, DBF4A Peptide, ZDBF1 Peptide, RGD1305854 Peptide, DBF4 Peptide, LOC100229596 Peptide, AA545217 Peptide, Ask Peptide, dbf4a Peptide, xdbf4 Peptide, ChDBF4 Peptide, DBF4 zinc finger Peptide, DBF4 zinc finger L homeolog Peptide, DBF4 Peptide, dbf4 Peptide, Dbf4 Peptide, dbf4.L Peptide
- Background
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Dbf4 is a regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Alias Symbols: AA545217, Ask
Protein Size: 662 - Molecular Weight
- 72 kDa
- Gene ID
- 27214
- NCBI Accession
- NM_001190717, NP_001177646
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