Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) Peptide
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- Target See all CXCL1 products
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCL1 antibody (Catalog #: AVARP07032_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
- Synonyms
- FSP Peptide, GRO1 Peptide, GROa Peptide, MGSA Peptide, MGSA-a Peptide, NAP-3 Peptide, SCYB1 Peptide, CINC-1 Peptide, Gro1 Peptide, CXCL1 Peptide, Sdf1 Peptide, Fsp Peptide, KC Peptide, Mgsa Peptide, N51 Peptide, Scyb1 Peptide, gro Peptide, GRO Peptide, Gro Peptide, C-X-C motif chemokine ligand 1 Peptide, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Peptide, C-X-C motif chemokine ligand 12 Peptide, chemokine (C-X-C motif) ligand 1 Peptide, CXCL1 Peptide, Cxcl1 Peptide, Cxcl12 Peptide, GRO1 Peptide
- Background
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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif.Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GRO1, GROa, MGSA, MGSA alpha, MGSA-a, NAP-3, SCYB1, FSP
Protein Interaction Partner: CXCR1,CXCL1,CXCR1,CXCR2,DARC,MMP9,CXCL1,DARC
Protein Size: 107 - Molecular Weight
- 8 kDa
- Gene ID
- 2919
- NCBI Accession
- NM_001511, NP_001502
- UniProt
- P09341
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