MRG-Binding Protein (MRGBP) Peptide
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- Target See all MRGBP products
- MRGBP (MRG-Binding Protein (MRGBP))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-C20ORF20 antibody (Catalog #: ARP33352_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRGBP (MRG-Binding Protein (MRGBP))
- Synonyms
- C20orf20 Peptide, Eaf7 Peptide, MRG15BP Peptide, URCC4 Peptide, c20orf20 Peptide, zgc:73167 Peptide, 1600027N09Rik Peptide, AW060503 Peptide, C80444 Peptide, MRG domain binding protein Peptide, MRG/MORF4L-binding protein Peptide, MRG-binding protein Peptide, putative mrg-binding protein Peptide, MRG/MORF4L binding protein Peptide, MRGBP Peptide, LOC5577096 Peptide, CpipJ_CPIJ006487 Peptide, CpipJ_CPIJ017611 Peptide, Smp_130630 Peptide, mrgbp Peptide, Mrgbp Peptide
- Background
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C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Alias Symbols: Eaf7, MRGBP, URCC4, MRG15BP, C20ORF20
Protein Interaction Partner: ACTB,ACTL6A,BRD8,DMAP1,ING1,MEAF6,MORF4L1,MORF4L2,RUVBL1,TRRAP,TUBB,YEATS4,BRD8
Protein Size: 204 - Molecular Weight
- 22 kDa
- Gene ID
- 55257
- NCBI Accession
- NM_018270, NP_060740
- UniProt
- Q9NV56
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