Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (N-Term) Peptide
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- Target See all AKR1B1 products
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1B1 antibody (Catalog #: ARP48179_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- Synonyms
- ADR Peptide, ALDR1 Peptide, ALR2 Peptide, AR Peptide, ALDRED Peptide, ALR-P-I Peptide, Akr1b3 Peptide, Akr1b4 Peptide, Aldr1 Peptide, Alr Peptide, RATALDRED Peptide, akr1b7 Peptide, zgc:86611 Peptide, aldo-keto reductase family 1 member B Peptide, aldo-keto reductase family 1, member B1 (aldose reductase) Peptide, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog Peptide, AKR1B1 Peptide, Akr1b1 Peptide, akr1b1.S Peptide, akr1b1 Peptide
- Background
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AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADR, ALDR1, ALR2, AR, MGC1804
Protein Interaction Partner: SMAD1,TFE3
Protein Size: 316 - Molecular Weight
- 36 kDa
- Gene ID
- 231
- NCBI Accession
- NM_001628, NP_001619
- UniProt
- P15121
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