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Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) Peptide

ADRB1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972963
  • Target See all ADRB1 products
    ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ADRB1 antibody (Catalog #: ARP36551_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
    Background
    The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 gene have been shown to affect the resting heart rate and can be involved in heart failure.The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR

    Protein Interaction Partner: ADRA2A,GIPC1,GPRASP1,GPRASP2,GRB2,SH3GL2,SH3GL3,ADRA2A,ARRB1,DLG1,DLG4,DLGAP2,GIPC1,GOPC,GPRASP1,GPRASP2,GRB2,MAGI2,MAGI3,NOS1,SH3GL2,SH3GL3,ARRB1,DLG4,GIPC1

    Protein Size: 477
    Molecular Weight
    51 kDa
    Gene ID
    153
    NCBI Accession
    NM_000684, NP_000675
    UniProt
    P08588
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