Adrenomedullin (ADM) (C-Term) Peptide
ADM
Reactivity: Human
Host: Synthetic
WB, BP
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- Target See all Adrenomedullin (ADM) products
- Adrenomedullin (ADM)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Adrenomedullin (ADM) peptide (KLH)
ADM Reactivity: Human Host: Synthetic WB, Imm, SDS
Adrenomedullin (ADM) peptide (Ovalbumin)ADM Reactivity: Human Host: Synthetic WB, Imm, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Adrenomedullin (ADM)
- Target Type
- Hormone
- Background
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Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
Alias Symbols: AM
Protein Interaction Partner: ADM,CALCRL,CFH,EDN1,MME
Protein Size: 185 - Molecular Weight
- 20 kDa
- Gene ID
- 133
- NCBI Accession
- NM_001124, NP_001115
- UniProt
- P35318
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