ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B) Peptide
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- Target See all ACTR1B products
- ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACTR1B antibody (Catalog #: ARP52099_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
- Synonyms
- ARP1B Peptide, CTRN2 Peptide, PC3 Peptide, 2310066K23Rik Peptide, AA960180 Peptide, AI851923 Peptide, Arp1b Peptide, ACTR1B Peptide, ARP1 actin related protein 1 homolog B Peptide, ARP1 actin-related protein 1B, centractin beta Peptide, ARP1 actin-related protein 1 homolog B Peptide, ARP1 actin-related protein 1 homolog B, centractin beta (yeast) Peptide, beta-centractin Peptide, ACTR1B Peptide, Actr1b Peptide, LOC100594459 Peptide
- Background
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ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.
Alias Symbols: ARP1B, CTRN2, PC3
Protein Interaction Partner: ACTA1,CHD3,DCTN1
Protein Size: 376 - Molecular Weight
- 42 kDa
- Gene ID
- 10120
- NCBI Accession
- NM_005735, NP_005726
- UniProt
- P42025
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