Endothelin 3 (EDN3) Peptide
EDN3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Endothelin 3 (EDN3) products
- Endothelin 3 (EDN3)
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LHFCTQTLDV SSNSRTAEKT DKEEEGKVRG ANRGLCQRRL KSRTNKASRL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of EDN3 antibody,
Alternative Names: EDN3 control peptide, EDN3 antibody Blocking Peptide, Anti-EDN3 Blocking Peptide, endothelin 3 Blocking Peptide, ET3 Blocking Peptide, MGC15067 Blocking Peptide, MGC61498 Blocking Peptide, EDN3, EDN-3, EDN 3, EDN-3 Blocking Peptide, EDN 3 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Endothelin 3 (EDN3)
- Background
- The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
- Molecular Weight
- 24 kDa
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