E3 ubiquitin-protein ligase RAD18 (RAD18) Peptide
RAD18
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all RAD18 products
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KQVTKVDCPV CGVNIPESHI NKHLDSCLSR EEKKESLRSS VHKRKPLPKT
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RAD18 antibody,
Alternative Names: RAD18 control peptide, RAD18 antibody Blocking Peptide, Anti-RAD18 Blocking Peptide, Rad18 Homolog Blocking Peptide, RNF73 Blocking Peptide, RAD18, RAD-18, RAD 18, RAD-18 Blocking Peptide, RAD 18 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Synonyms
- RNF73 Peptide, 2810024C04Rik Peptide, Rad18sc Peptide, zgc:55577 Peptide, RAD18 Peptide, DDBDRAFT_0218120 Peptide, DDBDRAFT_0304878 Peptide, DDB_0218120 Peptide, DDB_0304878 Peptide, DKFZp469H0810 Peptide, RAD18, E3 ubiquitin protein ligase Peptide, RAD18 E3 ubiquitin protein ligase Peptide, E3 ubiquitin-protein ligase RAD18 Peptide, E3 ubiquitin-protein ligase Peptide, DNA repair protein and ATPase Peptide, C3HC4-type zinc finger-containing protein Peptide, RAD18 Peptide, Rad18 Peptide, rad18 Peptide
- Background
- RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
- Molecular Weight
- 56 kDa
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