Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all PYHIN1 products
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KMKEEYDKIQ IADLMEEKFP GDAGLGKLIE FFKEIPTLGD LAETLKREKL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PYHIN1 antibody,
Alternative Names: PYHIN1 control peptide, PYHIN1 antibody Blocking Peptide, Anti-PYHIN1 Blocking Peptide, pyrin and HIN domain family, member 1 Blocking Peptide, IFIX Blocking Peptide, MGC23885 Blocking Peptide, RP11-520H16.1 Blocking Peptide, PYHIN1, PYHIN-1, PYHIN 1, PYHIN-1 Blocking Peptide, PYHIN 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Synonyms
- IFIX Peptide, RP11-520H16.1 Peptide, 4930422C14 Peptide, AI447904 Peptide, Ifi209 Peptide, Ifix Peptide, pyrin and HIN domain family member 1 Peptide, interferon activated gene 209 Peptide, PYHIN1 Peptide, Ifi209 Peptide
- Background
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
- Molecular Weight
- 51 kDa
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