Minichromosome Maintenance Deficient 4 (MCM4) Peptide
MCM4
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all MCM4 products
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KEELAEALKK LILSKGKTPA LKYQQLFEDI RGQSDIAITK DMFEEALRAL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MCM4 antibody,
Alternative Names: MCM4 control peptide, MCM4 antibody Blocking Peptide, Anti-MCM4 Blocking Peptide, Minichromosome Maintenance Complex Component 4 Blocking Peptide, MCM4, MCM-4, MCM 4, MCM-4 Blocking Peptide, MCM 4 Blocking Peptide - Purification
- Rabbit Anti-c-Jun (Ab-73) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
- Synonyms
- cdc21 Peptide, CDC21 Peptide, CDC54 Peptide, NKCD Peptide, NKGCD Peptide, P1-CDC21 Peptide, hCdc21 Peptide, 19G Peptide, AI325074 Peptide, AU045576 Peptide, Cdc21 Peptide, Mcmd4 Peptide, mKIAA4003 Peptide, mcdc21 Peptide, cb1025 Peptide, fc12c09 Peptide, fj85g09 Peptide, hm:zeh1616 Peptide, wu:fc12c09 Peptide, wu:fj85g09 Peptide, zeh1616 Peptide, minichromosome maintenance complex component 4 L homeolog Peptide, minichromosome maintenance complex component 4 S homeolog Peptide, minichromosome maintenance complex component 4 Peptide, mcm4.L Peptide, mcm4.S Peptide, MCM4 Peptide, mcm4 Peptide, Mcm4 Peptide
- Background
- The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRkDaC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
- Molecular Weight
- 95 kDa
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