Titin-Cap (Telethonin) (TCAP) Peptide
TCAP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TCAP products
- TCAP (Titin-Cap (Telethonin) (TCAP))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCAP antibody,
Alternative Names: TCAP control peptide, TCAP antibody Blocking Peptide, Anti-TCAP Blocking Peptide, Titin-Cap Blocking Peptide, Telethonin Blocking Peptide, CMD1N Blocking Peptide, LGMD2G Blocking Peptide, T-cap Blocking Peptide, TELE Blocking Peptide, telethonin Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TCAP (Titin-Cap (Telethonin) (TCAP))
- Background
- Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
- Molecular Weight
- 19 kDa
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