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TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide

TGIF1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938892
  • Target See all TGIF1 products
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of TGIF1 antibody,
    Alternative Names: TGIF1 control peptide, TGIF1 antibody Blocking Peptide, Anti-TGIF1 Blocking Peptide, Tgfb-Induced Factor Homeobox 1 Blocking Peptide, HPE4 Blocking Peptide, MGC39747 Blocking Peptide, MGC5066 Blocking Peptide, TGIF Blocking Peptide, TGIF1, TGIF-1, TGIF 1, TGIF-1 Blocking Peptide, TGIF 1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Synonyms
    HPE4 Peptide, TGIF Peptide, AA959811 Peptide, AI462167 Peptide, Tgif Peptide, Tfig Peptide, fa06h05 Peptide, fb33g11 Peptide, zgc:55852 Peptide, wu:fa06h05 Peptide, wu:fb33g11 Peptide, hpe4 Peptide, tgif Peptide, tgif1 Peptide, TGFB induced factor homeobox 1 Peptide, TGFB-induced factor homeobox 1 Peptide, TGFB induced factor homeobox 1 S homeolog Peptide, TGIF1 Peptide, Tgif1 Peptide, tgif1 Peptide, tgif1.S Peptide
    Background
    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
    Molecular Weight
    43 kDa
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